Arterial Stiffness

Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity Iva´n G. Horva´ tha, A´ da´m Ne´metha, Zso´ fia Lenkeya, Nicola Alessandrib, Fabrizio Tufanob, Pa´ l Kisa, Bala´ zs Gasznera and Attila Czira´ kia Background The importance of measuring aortic pulse wave velocity (PWVao), aortic augmentation index (Aix) and central systolic blood pressure (SBPao) has been shown under different clinical conditions; however, information on these parameters is hard to obtain. The aim of this study was to evaluate the accuracy of a new, easily applicable oscillometric device (Arteriograph), determining these parameters simultaneously, against invasive measurements. Methods Aortic Aix, SBPao and PWVao were measured invasively during cardiac catheterization in 16, 55 and 22 cases, respectively, and compared with the values measured by the Arteriograph. Results We found strong correlation between the invasively measured aortic Aix and the oscillometrically measured brachial Aix on either beat-to-beat or mean value per patient basis (rU0.9, P<0.001; rU0.94, P<0.001), which allowed the noninvasive calculation of the aortic Aix without using generalized transfer function. Similarly strong correlation (rU0.95, P<0.001) was found between the invasively measured and the noninvasively calculated central SBPao; furthermore, the BHS assessment of the paired differences fulfilled the ‘B’ grading. The PWVao values measured invasively and by Arteriograph were 9.41W1.8 m/s and 9.46W1.8 m/s, respectively (meanWSD); furthermore, the Pearson’s correlation was 0.91 (P<0.001). The limits of